Model organisms are used for research because they provide a framework on which to develop and optimize methods that facilitate and standardize analysis. Such organisms should be representative of the living beings for which they are to serve as proxy. However, in practice, a model organism is often selected ad hoc , and without considering its representativeness, because a systematic and rational method to include this consideration in the selection process is still lacking. In this work we propose such a method and apply it in a pilot study of strengths and limitations of Saccharomyces cerevisiae as a model organism. The method relies on the functional classification of proteins into different biological pathways and processes and on full proteome comparisons between the putative model organism and other organisms for which we would like to extrapolate results.
Box , Addis Ababa, Ethiopia. Bioethanol is one of the most commonly used biofuels in transportation sector to reduce greenhouse gases. This paper reviews the current and nonmolecular trends in ethanol production using S. Ethanol has been produced from wide range of substrates such as molasses, starch based substrate, sweet sorghum cane extract, lignocellulose, and other wastes. The inhibitors in lignocellulosic hydrolysates can be reduced by repeated sequential fermentation, treatment with reducing agents and activated charcoal, overliming, anion exchanger, evaporation, enzymatic treatment with peroxidase and laccase, in situ detoxification by fermenting microbes, and different extraction methods. Coculturing S.
Abstract The effect of different initial reducing sugar concentration on ethanol production in batch fermentation of Chuntian No. In addition, kinetic model was studied. With the increase of initial sugar concentration, a significant inhibition on the maximum specific growth rate was clearly observed, however, there was no significant influence on the maximum specific ethanol production rate. Hinshelwood model was successfully applied to describe the effects of different initial reducing sugar concentration on the kinetic parameters of ethanol fermentation by immobilized Saccharomyces cerevisiae CICC , using sweet sorghum stalk juice as the substrate. The kinetic parameters of fermentation process were obtained.
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