Delayed hemolytic transfusion reaction case study

The patient is a 54 year old woman, presenting to the Emergency Room with complaints of abdominal cramps and feeling lethargic for the past few days. She also reports her stools have been black and sticky. Her chart reveals a history of ulcers and GI bleeding. She was transfused with 2 units packed RBCs 2 months ago for the same symptoms. CBC results are shown below.
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Transfusion reactions--how to diagnose, manage, and avoid them (Proceedings)

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Final Diagnosis -- Case

A year-old African-American woman with a history of sickle cell disease presented for surgical evaluation of left total hip arthroplasty due to avascular necrosis of the femoral head. In anticipation of a complex orthopedic procedure, pre-surgical blood work was ordered. Although the patient had a history of anti-Fya, the antibody identification was inconclusive, so the workup was sent to a reference laboratory. The patient was last transfused with red blood cells RBCs 2 years earlier, but had no history of transfusion reactions. Due to surgery, the patient's hemoglobin Hb decreased from
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Final Diagnosis -- Hemolytic transfusion reactions caused by the Kidd blood group

Since the early s, the use of blood products in the treatment of critically ill companion animals and in supporting dogs and cats undergoing surgery and minimally-invasive diagnostic and therapeutic procedures has increased tremendously. Blood components are, however, prepared from donor animals and consequently represent a limited resource. This is despite the establishment of several commercial animal blood banks. Moreover, blood components are biologic products that possess the inherent ability to cause transfusion reactions.
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A year-old African-American woman with a history of sickle cell disease presented for surgical evaluation of left total hip arthroplasty due to avascular necrosis of the femoral head. In anticipation of a complex orthopedic procedure, pre-surgical blood work was ordered. Although the patient had a history of anti-Fya, the antibody identification was inconclusive, so the workup was sent to a reference laboratory.
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